We also found upregulated HLA-A heavy chain in high HLA class I expression cell lines QGY7701 and BEL7405 and lacked the expression of LMP2 and LMP7 in low HLA class I expression cell line BEL7404 by real-time PCR.
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- 在HLA I類(lèi)分子表達下調的細胞系BEL7404中,HLA重鏈、輕鏈及TAP分子均表達正常,存在蛋白酶體復合物亞單位LMP2表達減少,LMP7表達缺失。