Three kinds of food additive citric acid were produced by (1) TRPO, (2) by TBP and (3) by the calcium salt method. Their LD50 were 8250 mg/kg, 12 100 mg/ kg and 6520 mg kg respectively, in female rats when the drug was administered by gayage.
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- 檸檬酸(1)、(2)、(3)分別由三烷基氧膦(TRPO)萃取法、磷酸三丁酯(TBP)萃取法和鈣鹽法生產(chǎn)所獲產(chǎn)品,其對雌性大鼠經(jīng)口的LD_(50)分別為8250 mg/kg、12 100 mg/kg、5620mg/kg,均屬實(shí)際無(wú)毒類(lèi)食品添加劑。