This effect makes it possible to eliminate all tumor cells despite only a fraction of them expressing HSV1 -tk gene. In this study, A fusion gene encoding both HSV1-TK and hygromycin phosphotransferase was used as the therapeutic gene.
英
美
- 本研究用一種與潮霉素磷酸轉移酶基因(hygromycinphosphotransferase gene,hph)相融合的HSV1-tk基因作為目的基因(稱(chēng)為HyTK基因),構建了重組逆轉錄病毒載體LNCHyTK;