The typical method of ES cells differentiation into neural cells in vitro includes embryoid bodies (EBs) formation and subsequent differentiation into neural cells under all-trans retinoic acid or serum-free conditions.
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- ESCs體外誘導為神經(jīng)細胞的經(jīng)典途徑是先通過(guò)擬胚體階段以啟動(dòng)分化,再通過(guò)RA或無(wú)血清培養法誘導擬胚體分化為神經(jīng)細胞。