The synergistic effects of LPS, BLP and bacterial DNA were further examined in vitro at the level of PRRs on the cell surface of effector cells using cultured primary alveolar macrophages.
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- 通過(guò)體外實(shí)驗,從效應細胞表面病原菌相關(guān)模式識別受體(CD14、TLR4、TLR2、TLR9)水平進(jìn)一步觀(guān)察了細菌LPS、BLP和CpG-ODN對天然免疫細胞的協(xié)同刺激效應及其可能機制。