The results of electrochemical study indicate that with the effect of gold nanoparticles, DTIC could sensitively detect the single base mismatch of the DNA sequence, and gold nanoparticles can significantly improve its detection sensitivity.

 
  • 研究結果表明,DTIC作為分子探針可以很好地識別DNA鏈中存在的單堿基錯配,并且金納米粒子能夠大幅度地提高單堿基錯配的檢測靈敏度。
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