The present studyindicates that McAb AU1~1 against cervical carcinoma can mediate ADCC of splenocytes,peritoneal macrophages and LAK to U14 cells, suggests that its ability to direct ADCC make thisantibody promising candidate for cervical cancer therapy.
英
美
- 該研究表明針對宮頸癌細胞的單克隆抗體AU_(14-1)能通過(guò)ADCC發(fā)揮淋巴樣細胞、巨噬細胞及LAK細胞對靶腫瘤細胞的殺傷作用; 提示特異性宮頸癌單克隆抗體AU_(14-1)介導的抗體依賴(lài)細胞介導細胞毒(ADCC)在治療宮頸癌中可能是一種有希望的方法。