The phosphorylation of G protein-coupled receptor (GPCR) by G protein-coupled receptor kinases (GRKs) under the stimulation with their specific agonists is the critical step to desensitization of GPCR.

 
  • 激動(dòng)劑誘導的G蛋白偶聯(lián)受體激酶(GRK)對G蛋白偶聯(lián)受體(GPCR)的磷酸化是受體脫敏的關(guān)鍵步驟。
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