The metronidazole-loaded pellets showed a kind of dissolution phenomenon similar to pulsed and CSDDS, while formulated with 3% L-HPC as disintegrant and coated by 25% Eudragit S 100 and 15% DEP as Plasticizer.

 
  • 在Eudragit S100增重25%25、增塑劑用量為15%25、L-HPC 用量為3%25時(shí)具有較好的結腸靶向脈沖釋放效果。
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