The main role of MMP in angiogenesis, tumor growth and metastasis is degradation of extracellular matrix (ECM) and release and/or activation of growth factors through their degradative activity.
英
美
- 在血液系統惡性腫瘤中，白血病的浸潤過(guò)程是多基因、多步驟、多階段相互作用的級聯(lián)反應,其中基質(zhì)金屬蛋白酶介導的細胞外基質(zhì)及基底膜的降解過(guò)程,是腫瘤侵襲轉移的一個(gè)關(guān)鍵步驟。
