The kindled rats received AEDs treatment, that is the maximal human adult dosage of carbamazepine (CBZ), valproate (VPA), and topiramate (TPM)(n =6 for each group), and NS (n=5) administered as monotherapy to different groups of kindled rats for 1 month.

 
  • 方法 將60只SD大鼠隨機分為實(shí)驗組55只和空白組5只,參照Racine點(diǎn)燃分級標準,實(shí)驗組每間隔84h肌注閾下刺激(1ml/kg,每1ml馬桑內酯注射液含10g生藥材提取物)的CL至點(diǎn)燃,空白組予同體積生理鹽水肌注。
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