The inhibitory effect of the extract from SGY on contractility of isolated rat colonic smooth muscle strips may be associated with blocking VDC,ROC and SOC to prevent the calcium influx as well as to prevent the release of intracellular calcium.
英
美
- 疏肝飲具有抑制大鼠結腸平滑肌收縮的作用,機制可能涉及通過(guò)阻斷電壓門(mén)控鈣通道(VDC)、受體操縱性鈣通道(ROC)和鈣庫調控性鈣通道(SOC)抑制胞外Ca2+內流,同時(shí)涉及抑制胞內Ca2+的釋放。