The hyperinsulinemia and IR may be caused by a beta-cell hypersecretory response to the defective Peripheral sensitivity of insulin and by a decreased hepatic IS clearance with possibly increased urinary CP excretion.

 
  • 其發(fā)生原因與組織對胰島素的敏感性降低、胰島素分泌異常增多以及胰島素經(jīng)肝臟降解減少有關(guān),后者很可能伴有C肽經(jīng)腎臟排泄增多。
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