The findings indicate that LOH at MCC, DCC and YNZ22 loci may beinvolved in carcinogenesis of colorectal cancer, and LOH of DCC is frequently a late event intumor progression.

 
  • MCC、DCC基因和YNZ22位點(diǎn)的LOH與大腸癌發(fā)生、發(fā)展有關(guān),DCC基因LOH多為大腸癌的晚期改變。
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