The disorder of calcium ion and the accumulation of unfolded protein can lead to ER stress and thus induce a protective response-unfolded protein response (UPR).

 
  • 內質(zhì)網(wǎng)中鈣離子紊亂和未折疊蛋白質(zhì)蓄積可引發(fā)內質(zhì)網(wǎng)應激(endoplasmic reticulum stress, ERS),發(fā)生具有保護作用的未折疊蛋白反應(unfolded protein response, UPR)。
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