The amino acid sequence in all of these 6 clones is the same,HYEFWAWNWEAN, which is hydrophobic as N terminal of C34.Conclusion This phage display peptide can mimic the epitope of HIV 1 gp41 CHR ,and bind with HIV 1 gp41 NHR.
英
美
- 上述 6個(gè)陽(yáng)性克隆經(jīng)DNA測序 ,氨基酸序列相同 :HYEFWAWNWEAN ,其明顯的疏水性質(zhì)類(lèi)似于C34N末端 ,特異性鑒定顯示這些克隆均能夠與HIV 1gp4 1N多肽結合。 結論 該噬菌體克隆展示肽可模擬HIV 1gp4 1CHR多肽表位 ,并可與N多肽結合
