The NTFs are imperative to the survival, growth and differentiation of important neuronal populations in the peripheral and central nervous systems.

 
  • NGF必須與高親和力受體TrkA結合才能發(fā)揮作用,通過(guò)一系列細胞內的信號傳導途徑影響靶細胞的生長(cháng),凋亡,分化和侵襲潛能。
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