The DSH locus has recently been mapped to chromosome Iq11-q21 and pathogenic mutations were identified in ADAR, the gene encoding double-stranded RNA-specific adenosine deaminase, in Japanese patients with DSH.
英
美
- 日曬后皮損加重,一般無(wú)自覺(jué)癥狀。 國內張學(xué)軍等首先將DSH致病基因定位于染色體1q11-q21,日本學(xué)者新近證明DSH是由該區ADAR基因突變所致。