The DNA adduct formation and cytochrome P450 1A1 (CYP1A1) induction have been suggested to be the major determinant of their carcinogenic activity.

 
  • 已知多環(huán)芳香烴對細胞色素P450 1A1 (CYP1A1) 之誘發(fā)能力和形成DNA鍵結物以及引起腫瘤形成呈正相關(guān)性。
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