The CpG-ODNs included the optimal motifs: the ODN-1826 (GACGTT) and -2006 (GTCGTT) for the mice and humans cells, the ODN-1670 (AACGTT) used in Atlantic salmon, the ODN-D containing two repeats motif of those in 1670 and the ODN-R with an inverted CpG.

 
  • 實(shí)驗中采用了含不同CpG motif的序列:在小鼠和人中有良好刺激作用的最適序列ODN-1826(GACGTT)和ODN-2006(GTCGTT); 在大西洋鮭中有刺激活性的ODN-1670(AACGTT);
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