Tankyrase, a new telomeric poly (ADP ribose) polymerase (PARP), acts as a positive regulator of telomere elongation. It can influence chromosomal stability and is closely related to cell senescence, death and carcinogenesis.
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- 端錨聚合酶 (tankyrase)是一種位于端粒的聚腺苷二磷酸核糖聚合酶 ,它在端粒酶陽(yáng)性細胞中過(guò)表達可使端粒長(cháng)度增加 ,從而影響染色體的穩定性 ,與細胞的衰老、死亡和癌變密切相關(guān) ;