Recent studies have found that p16 and p21, the specific suppressors of cyclin/CDK4/6, can regulate the phosphorylation of pRb and control the cell cycle progression through p16 - cyclm/CDK - Rb and p53 - p21 - cyclin/CDK - Rb pathway.
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美
- 近年來(lái)的研究發(fā)現，許多基因通過(guò)信號傳導途徑調節pRb發(fā)生細胞周期依賴(lài)性磷酸化。 其中被廣泛研究的是p16-cyclin/CDK-Rb途徑和p53-p21-cyclin/CDK-Rb途徑。
