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- Objective To observe the expression of RNA editing deaminase ADAR2(RED1),ADAR3(RED2)mRNA on various degree malignant glioma cell lines. 目的觀(guān)察不同惡性程度的膠質(zhì)瘤細胞中RNA編輯酶ADAR2(RED1),ADAR3(RED2)mRNA水平的表達。
- The expression of RNA editing deaminase ADAR2,ADAR3 mRNAon human glioma cell lines 膠質(zhì)瘤中RNA編輯酶ADAR2,ADAR3 mRNA表達及意義
- Keywords RNA editing deaminase,cellular translocation,transient transfection,Western blotting,isoforms of protein,ADAR1; RNA編輯酶;細胞內轉位;瞬時(shí)轉染;免疫印跡;蛋白亞型;ADAR1;
- ADAR belongs to a family of RNA-specific adenosine deaminase that represents one type of RNA editing enzyme and encodes double-stranded RNA-specific adenosine deaminase. 該酶是RNA編輯酶中的一類(lèi),能夠特異性的修飾雙鏈RNA結構和mRNA前體,將特殊位點(diǎn)上的腺嘌呤核苷(A)轉換成次黃嘌呤核苷(I),導致雙鏈RNA結構不穩定及mRNA降解,并產(chǎn)生特定的生理效應。
- Trypanosome belonging to kinetoplastid protozoa is host to a variety of intriguing and unique features,including RNA editing. 錐蟲(chóng)做為動(dòng)基體目原蟲(chóng)擁有許多有趣的生化特性,RNA剪輯即是其中之一。
- ADAR (adenosine deaminases acting on RNA) is involved in site-selective RNA editing that changes adenosine residues to inosine in double-stranded RNA (dsRNA) and messenger RNA (mRNA). ADAR是一種雙鏈RNA特異性腺苷酸脫氨酶,主要生物學(xué)功能包括RNA編輯和誘導蛋白質(zhì)在核內的翻譯。 它能夠作用于特定雙鏈RNA結構和mRNA前體,將特殊位點(diǎn)上的腺苷(A)去氨基轉變?yōu)榇吸S嘌呤(I),導致雙鏈RNA結構不穩定及mRNA的降解。
- Then along came RNA editing, in which guide RNAs or enzyme action modify some messenger RNAs such that the final protein sequence cannot be deduced from the gene sequence alone. 但RNA編輯又來(lái)?yè)v亂了:向導RNA和酶作用于信使RNA的修飾過(guò)程,這就使僅僅從基因序列來(lái)推斷最終的蛋白序列成為不可能。
- The editing of the manuscript is now in hand. 這部手稿的編輯工作現在已經(jīng)開(kāi)始。
- He spent all morning editing the book. 他整個(gè)上午都在編寫(xiě)該書(shū)。
- Keywords Diet therapy;Epilepsy;Receptor, glutamate;Mossy fiber, hippocampus;RNA editing;cognitive function; 膳食療法;癲癇;受體;谷氨酸;苔蘚纖維;海馬;RNA編輯;認知功能;
- He edit a daily paper before he come to teach at our college. 他來(lái)我們學(xué)院任教之前充任過(guò)一份日報的主編。
- He spent his last years (in) teaching and editing earlier writings. 他把晚年用在教書(shū)和編纂以前的著(zhù)作。
- The editing of film or recording tape. 剪輯電影的剪輯或音帶的錄制
- A sequence of RNA produced by transcription. 轉錄一個(gè)經(jīng)轉錄合成的rna的序列
- DNA and RNA are both types of nucleic acid. 脫氧核糖核酸和核糖核酸是兩種類(lèi)型的核酸。
- I spent two days writing and editing the piece. 我花了兩天時(shí)間來(lái)寫(xiě)作、編輯這篇文章。
- Work in understanding the role of RNA in the cell. 對核糖酸(rna)細胞中作用認識的研究。
- All RNA phages cause the death of the host cell. 所有的RNA噬菌體導致寄主細胞死亡。
- To subject(messenger RNA) to translation. 轉移使(核糖核酸信息)被轉譯
- Could RNA interfere with prion disease? RNA能否干預普粒子疾???