Plasmid of HBV DNA dimer was transfected into a differentiated human hepatoma cell line(HepC2), and a stable HBV-producing cell line(z7-4) was set up which had capable of secreting HBcAg/HBeAg,viral nucleic acids and of releasing Dane-like particles.

 
  • 用HBV DNA二聚體轉染高度分化的人肝癌細胞株(HepG2),篩選出具有分泌病毒抗原、核酸以及釋放42nm Dane顆粒能力的z7-4細胞株。
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