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- Rat Phosphotylinosital 3 kinase，PI3K Elisa Kit... 大鼠磷酸肌醇3激酶（PI3K）試劑盒；
- In the integrin-signal transduction pathway which FAK is central, except for the ras-MAPK pathway, there are also phosphatidylinositol-3-kinase (PI3K) and protein kinase B (serine/threonrine kinase, AKT) signal molecules. 以FAK為中心的整合素信號轉導通路除了ras-MAPK信號途徑外,還有磷脂酰肌醇-3激酶(phosphatidylinositol 3-kinase, PI3K)和蛋白激酶B即AKT(serine/threonrine kinase,AKT)信號分子的參與。
- The insulin works by switching on cellular signaling proteins called kinases (specifically Src, PI3K, and Akt) and a protein (SREBP) that binds elements in DNA that regulate the production of cholesterol and its relatives. 胰島素功能在于激活一類(lèi)叫作激酶的細胞信號蛋白（特定的致敏反應細胞，如磷脂酰肌醇(-3)激酶,蛋白激酶B等）以及一種DNA元素結合蛋白（膽固醇調節元件結合蛋白），這種蛋白質(zhì)能調節膽固醇及類(lèi)膽固醇的生成。
- The lipid kinase phosphoinositied 3-OH kinase(PI3K) and its downstream target AKT,that is protein kinase B(PKB),plays important roles in carcinogenesis signal pathway reduced by kinds of PTK receptor. 脂類(lèi)激酶PI3K和它的下游靶點(diǎn)Akt,即蛋白激酶B,在各種酪氨酸激酶受體誘導的致癌信號通路中發(fā)揮了重要的作用。
- Low-expression of PTEN protein may stimulate overexpression of PI3K protein. PTEN表達的缺失可能刺激了PI3K蛋白的強陽(yáng)性表達。
- Kenyan buyer requires suspension parts for mtor vehicles, clutches and pressure plates, silicone andar care products, motorcycle helmets, brake pads, fan belts, etc. Korean supp. 中文內容:我方求購韓國產(chǎn)的汽車(chē)配件,主要有:離合器,壓力器,摩托車(chē)頭盔,剎車(chē)等。有意者,請郵寄目錄表及價(jià)目表!
- The phosphorylation of Akt and FAK were dramatically attenuated in cells treated with rosiglitazone. 由于FAK和Akt都是抑癌基因PTEN（phosphatase and tensin homolog deleted on chromosome ten）的下游信號分子，因此我們檢測了ROS對PTEN的影響，結果發(fā)現ROS可以上調PTEN蛋白質(zhì)，而且這種上調作用具有劑量和時(shí)間依賴(lài)性；
- Liu Yi,He Yikang,Qin Feng,et al.Investigation of mtor saliency tracking based sensorless vector control drive for PMSM[J].Proceedings of the CSEE,2005,25(17):121-126(in Chinese). [7]劉毅;賀益康;秦峰;等.;基于轉子凸極跟蹤的無(wú)位置傳感器永磁同步電機矢量控制研究[J]
- In wild-type adult mice, the mTOR activity was suppressed and new protein synthesis was impaired in axotomized RGCs, which may contribute to the regeneration failure. 而且，在存活下來(lái)的樣本中，多達10%25顯示出了明顯的神經(jīng)軸突再生。這種再生隨時(shí)間延長(cháng)而不斷增加。
- We know that glutamate activates mGluR and PI3K, but we don't know how, he said. 我們知道谷氨酸激活親代謝性谷氨酸鹽受體和PI3K，但并不知道機理，他說(shuō)到。
- However, interfering with PI3K signaling might increase the risk of bacterial infections in humans. 但是干擾PI3K信號通路可能會(huì )增加患者細菌感染的機會(huì )。
- Methods: Immunohistochemistry(SP method) was adopted to detect PTEN and PI3K protein expression levels. 方法:采用免疫組織化學(xué)SP法檢測PTEN與PI3K的蛋白表達。
- Results: PTEN and PI3K proteins positive rates were 55.93%(33/59) and 77.97%(46/59) respectively in 59 NSCLC. 結果：NSCLC組織中PTEN、PI3K蛋白的陽(yáng)性表達率分別為55.;93%25(33/59)、77
- Howeer, interfering with PI3K signaling might increase the risk of bacterial infections in humans. 但是干擾PI3K信號通路可能會(huì )增加患者細菌感染的機會(huì )。
- Akt is one of Ser (serine)/Thr (threonine) protein kinases, which occupies hinge location in these signal transductions. Akt2 is one member of Akt family. Akt是一種絲氨酸/蘇氨酸蛋白激酶，處于該信號轉導的樞紐部位，Akt2是Akt的亞型之一，更多地參與了人類(lèi)腫瘤的發(fā)生和發(fā)展。
- Conclusion: The pathway of signal transcription after insulin receptor can be affect by leptin through PI3K pathway. PI3K途徑 Part 1 Expression and Distribution of the Functional Leptin Receptor mRNA Objective Leptin receptor is a recently identified hormonal product; encoded by the diabetic(db) gene .
- Here we report that AKT associates with NFAR1 in vivo with colocalization in the nucleus of the cell.Experiments in vitro and in vivo shows AKT phosphorylates NFAR1 on Serine 647. 在本文中證實(shí)了AKT與NFAR1相互作用的，并共定位于細胞核，并用體外實(shí)驗和體內實(shí)驗證明了AKT確實(shí)可以磷酸化NFAR1的S 647位。
- Activation of the PI3K pathway in cancer through inhibition of PTEN by exchange factor P-REX2a. 通過(guò)激活抑癌基因PTEN在抑制癌細胞PI3K途徑通過(guò)交換因子的P - REX2a。
- Decrease of AKT phosphorylation affects the activity of glucose transporter-4（GLUT-4） which translocates the glucose into cells, so the level of blood glucose increases. AKT磷酸化的降低即活性的降低導致葡萄糖轉運因子4（Glucose Transporter-4，GLUT-4）的活性降低，最終影響血液中葡萄糖向細胞內的轉運，表現出血糖升高的生理現象。
