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- The protein binding selectivity of clozapine was discussed. 討論了氯氮平蛋白結合作用的選擇性。
- OBJECTIVE To study the plasma protein binding rate of harmine hydrochloride. 目的:測定鹽酸去氫駱駝蓬堿的血漿蛋白結合率。
- Competitive protein binding assay indicates the level of cAMP is improved when CDCA is given by oral administration. 通過(guò)競爭性蛋白質(zhì)結合分析法測得，鵝去氧膽酸經(jīng)灌胃給藥后能顯著(zhù)提高大白鼠氣管組織中cAMP的含量。
- Method H?3?cAMP was used in protein binding assay to determine the level of cAMP in bovine BTC. 方法運用蛋白競爭結合法用氚（H3）標記的環(huán)磷酸腺苷（adenosine3，5?cyclicmonphos?phate，cAMP）測定牛眼小梁細胞內cAMP的含量。
- Methods: Activity of PKC was determined by using competitive protein binding method. 方法:應用競爭蛋白結合法檢測PKC活性。
- Drug protein binding changes involved in numerous factors in vivo may cause changes of pharmacokinetic parameters. 體內各種因素引起的藥物與血漿蛋白結合的改變,可能導致相應的藥代動(dòng)力學(xué)參數變化。
- Hypocalcaemia (low calcium) is also seen due to poor absorption of vitamin D and calcium, and secondary to low protein binding of calcium. 低血鈣有時(shí)也會(huì )發(fā)生，因為維生素D和鈣質(zhì)的吸收不良和低蛋白結合鈣。
- A major role: Botox is the world's recognized best wrinkle agent, a protein binding Biochemical Technology, safe and effective, no side effects. 主要作用：肉毒桿菌素是當今世界公認的最佳除皺劑，屬蛋白結合生化科技，安全有效，絕無(wú)副作用。
- The content and speciation analysis of protein binding speciation of trace elements Fe,Zn,Cu,Mn in the pollens of rape,maize,tea and lotus were studied by AAS. 以油菜、玉米、茶及蓮花粉為實(shí)驗材料 ,應用原子吸收分光光度法測定了 4種花粉中微量元素 Fe、Zn、Cu、Mn的蛋白質(zhì)結合態(tài)含量及形態(tài)分布。
- Because the problems associated with protein binding are more prevalent in lateral-flow assays, this article will focus especially on issues relating to such systems. 因為在側向流動(dòng)試劑中，關(guān)于蛋白固定的問(wèn)題很普遍，所以這篇文章主要集中這些系統相關(guān)的問(wèn)題。
- The likelihood of interactions is low due to limited metabolism and plasma protein binding and almost complete renal elimination of unchanged lamivudine. 由于有限的代謝和血漿蛋白結合，相互作用的可能性很低，因為不變拉米夫定幾乎完成腎臟消除。
- Results: The serum NPSH decreases markedly in children with diarrhea and pneumonia, the total sulfhydryl and protein bind sulfhydryl do not change obviously. 結果：表明肺炎及腹瀉患兒血清NPSH明顯降低，總巰基和蛋白結合巰基無(wú)明顯改變。
- After renaturation, AIF protein binded DNA and induced nuclear apoptosis. 經(jīng)EMSA與Hoechst 33258染色實(shí)驗證實(shí):獲得的AIF蛋白具有良好地與DNA結合并可誘導腫瘤細胞核凋亡的能力,凋亡率為37%25。
- The pharmacokinetic profile of Lev closely approximates the ideal characteristics expected of an antiepileptic drug, with good bioavailability, linear and time-invariant kinetics, minimal protein binding, and least metabolism. 左乙拉西坦幾乎具備了較好的抗癲癇藥物的所有藥動(dòng)學(xué)特性：生物利用度高、線(xiàn)性曲線(xiàn)、低蛋白結合率、無(wú)肝酶誘導作用。
- After the preparation of this compound, the kinetics of blood clearance in rabbits, biodistribution in mice, measurement of plasma protein binding rate, and myocardial perfusion imaging in dog were carried out. 其內容包括 :99m Tc- Q3在兔體內的血藥清除動(dòng)力學(xué)、血漿蛋白結合率、小鼠體內分布、家犬顯像及異常毒性試驗等。
- Alkaline phosphatase(ALP),osteocalcin or bone Gla-containing protein(BGP)and cyclic adenosine monophosphate (cAMP)levels were measured by chemical method,radioimmunoassay and competitive protein binding method,respectively. 采用“金氏”化學(xué)法、放射免疫法和競爭蛋白結合法測定堿性磷酸酶(ALP)、骨鈣素(BGP)和環(huán)磷酸腺苷(cAMP)濃度;
- OBJECTIVE:In this paper, the principle, feature and its application to the protein binding study of chiral drugs by High performance capillary electrophoresis /frontal analysis (HPCE/FA) are reviewed. 目的:綜述了高效毛細管電泳/前沿分析(HPCE/FA)方法的原理、特點(diǎn)、及其在手性藥物-蛋白結合研究中的應用。
- Protein Binding The plasma protein binding of tranexamic acid is about 3% at therapeutic plasma levels and seems to be fully accounted for by its binding to plasminogen (does not bind serum albumin). 治療水平的氨甲環(huán)酸蛋白結合率大概在3%25左右，應該大多數都是與纖溶酶原蛋白相結合的。
- The studies revealed that the resistance formation of rice stem borer was closely involved with the increase of detoxifying enzyme activity,target enzyme insensitivity and protein binding. 已有研究表明:解毒酶活性升高、靶標不敏感性以及蛋白質(zhì)的螯合作用與二化螟抗藥性形成的關(guān)系密切。
- DNA helix can have subtle structural variations in its grooves and its physical arrangement that affect how well proteins bind to it. 在其凹槽和物理排列方面，DNA螺旋可以有微妙的結構變化，從而可以影響蛋白與之結合的程度。
