Our previous work showed that HTV can lethally infect newborn suckling mice, the viral antigen and RNA can be detected in the cytoplasm of neurons in cerebral cortex and hippocampus, as well as Purkinje cell of cerebella cortex.

 
  • 本實(shí)驗首先建立了乳小鼠、乳大鼠大腦皮層神經(jīng)元體外培養的體系,以此作為病毒感染的靶細胞,在體外對HTV在腦皮層神經(jīng)元中的感染以及病毒感染對神經(jīng)元的影響進(jìn)行初步研究。
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