Objective:To study the Sibelium(Flunarizine) reverses antiepileptic drugs(AEDs)- induced overexpression of multidrug resistance gene (MDR1). Methods: Phenobarbital and Valproic acid were added into astrocytes and cultured permanently for 30 days.
英
美
- 目的 研究西比靈逆轉抗癲癇藥(AEDs)誘導的星形膠質(zhì)細胞多藥耐受基因(MDR1)表達的規律。