Objective: To study the effects of PolyI:C (Polyinosinic polycytidylic acid) on the incidence of diabetes and insulitis in the NOD (non-obese diabetic) mice, and change of Fas/ FasL protein and mRNA expression in pancreatic cells.
英
美
- 目的:觀(guān)察免疫調節劑聚肌苷酸胞嘧啶核苷酸(PolyI:C,Polyinosinic polycytidylic)對自然發(fā)病的非肥胖性糖尿病(Non-obese diabetic,NOD)小鼠糖尿病發(fā)生和胰島炎程度的影響以及干預后胰腺細胞Fas和Fas配體(FasL)的表達變化情況。