Normal cells respond to ER stress by increasing transcription of genes encoding ER-resident molecular chaperones such as GRP94, GRP78 and PDI to facilitate protein folding.

 
  • 細胞對這種應激的反應是增加一系列內質(zhì)網(wǎng)分子伴侶如GRP94、GRP78和PDI等的表達。
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