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- OBJECTIVE To provide a process for preparing nefiracetam used as an agent for improving cerebral function. 目的合成腦功能改善藥奈非西坦并改進(jìn)合成工藝。
- With 2,6-xylidine as starting material,Nefiracetam,a nootropic was synthesized by N-acylation and N-alkylation.Nefiracetam's structure was confirmed by element analvsis.IR.MS spectra and 1HMNR. 以2,6-甲基苯胺為起始原料,經(jīng)N-?；蚇-烷基化反應合成了促智藥奈非西坦,結構經(jīng)元素分析、紅外、質(zhì)譜、核磁共振氫譜確證,總收率65%25。
- Keywords nefiracetam;2;6-xylidine;synthesis;alzheimer s dementia; 奈非西坦;2;6-二甲基苯胺;合成;阿爾茨海默氏早老性癡呆;
- Keywords nefiracetam;condensation;synthesis;2;6 xylidine; 奈非西坦;縮合;合成;2;6-二甲基苯胺;
- Keywords nefiracetam nootropic synthesis alazheimer's disease; 奈非西坦;促智藥;合成;阿爾茨海默氏病;
- Keywords nefiracetam;related substances;high performance liquid chromatography; 奈非西坦;有關(guān)物質(zhì);高效液相色譜法;
- Keywords nefiracetam;sodium carbonate;2-chloro-N-（2;6-dimethyl） phenyl acetamide;2-pyrrolidone;sodium ethoxide; 奈非西坦;碳酸鈉;2-氯-N-（2;6-二甲基苯基）乙酰胺;2-吡咯烷酮;乙醇鈉;
- nefiracetam 奈非西坦
