Methods: B16F10 melanoma cells were inoculated,sc,iv and ip respectively into mice to establish 3 melanoma and lung metastasis models. Effect of DTIC,an anti-melanoma drug,on the 3 animal models was investigated.

 
  • 方法:分別通過(guò)皮下、靜脈和腹腔注射方式,將B16F10黑素瘤細胞接種于小鼠體內,建立3種黑素瘤及其肺轉移小鼠模型,并以達卡巴嗪作為試藥,考察其對這3種模型小鼠的作用。
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