Methods Coronary blood flow (CBF) intra-arterial blood pressure, heart rate, and coronary vascular resistance (CVR) were measured at rest, during isometric exercise before and 60 min after Losartan (25 mg/kg, ig).

 
  • 結果發(fā)現 ,Losartan明顯降低高血壓大鼠的平均動(dòng)脈壓和冠狀動(dòng)脈阻力 ,明顯增加其冠狀動(dòng)脈血流量 ,而對其心率無(wú)明顯影響 ;
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