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- The high performance capillary electrophoresis (HPCE) method was established for determining the optical purity of (+) and (-) meptazinol hydrochloride. 建立測定美普他酚對映體的毛細管區帶電泳法,代替國外HPLC手性柱的方法,用于檢測左旋體和右旋體的光學(xué)純度。
- The routine has been improved for the industrial production.The structure of meptazinol hydrochloride was confirmed by IR, UV, 1HNMR, 13CNMR, MS and DSC. 經(jīng)元素分析、IR、UV、1HNMR、13CNMR、MS和DSC等分析測試確定鹽酸美普他酚結構,HPLC含量測定大于99.;6%25。
- During the preparation of these bivalent candidates, the key step is the demethylation of (+)-meptazinol to give (+)-N-demethyl-meptazinol.Several methods were employed to demethylate meptazinol. 將雙配基設計的方法用于美普他酚,以鎮痛活性更優(yōu)的(+)-美普他酚為母體,設計并合成了六個(gè)不同長(cháng)度烴鏈連接的(+)-去甲美普他酚雙配基。
- Meptid 甲氮卓酚, 消痛定, 美他齊諾, 美他西諾[鎮痛藥]
- meptazinol hydrochloride 鹽酸美他齊諾
- Meptazinol 甲氮草酚, 消痛定