Materials and Methods: Uslng cyclic anhydride DTPA as a bifunctional chelat1ng a- gent, Gd3+ was attached to a monoclnal antihody (3D3).
英
美
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材料與方法:用DTPA環(huán)二酸研與抗肺癌單抗3D3和Gd3~3+分別偶聯(lián),制備出Gd-DTPA-IgG:建立6只荷瘤裸鼠模型; 將Gd-DTPA-IgG按2mg單抗/只的劑量從尾靜脈內注入;
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