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- Objective To elucidate the multidrug resistance(MDR) in bladdertransitional cell carcinoma. 目的研究膀胱移行細胞癌的多藥耐藥性。
- However, multidrug resistance (MDR) presents an important obstacle for the success of the treatment. 對瘤組織而言,多藥耐藥是化療失敗的主要原因。
- However,the multidrug resistance (MDR) of nasopharyngeal carcinoma is the key role in the failure of the treatment. 而多藥耐藥(MDR)機制是導致其化療等綜合治療失敗的主要原因。
- Conclusions The multidrug resistance (MDR) in endometrial carcinoma may be related with the expression of MDR1 gene. 結論子宮內膜癌對化療的耐藥可能是一種固有性MDR,這可能與MDR1基因的表達有關(guān)。
- Objective To study the relationship between p16,bcl 2 expression and multidrug resistance (MDR) in adenocarcinoma of colon. 目的 研究大腸腺癌p16、bcl-2 表達與多藥耐藥性的關(guān)系。
- Objective To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in MCF7/ADR and its mechanism. 目的:研究屈洛昔芬(DRO)對乳腺癌耐藥細胞株(MCF7/ADR)多藥耐藥性(MDR)的影響。
- Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely. 腫瘤多藥耐藥(MDR)是近年來(lái)腫瘤治療研究的困擾之一,其產(chǎn)生機制非常錯綜復雜。
- Abstract: Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely. 摘要: 腫瘤多藥耐藥(MDR) 是近年來(lái)腫瘤治療研究的困擾之一,其產(chǎn)生機制非常錯綜復雜。
- Multidrug resistance (MDR) is the most common cause in the failure of cancer chemotherapy.Drug transporters play an important role in multidrug resistance in cancer. 多藥耐藥性(MDR)是腫瘤化療失敗的最常見(jiàn)原因,藥物轉運蛋白在腫瘤多藥耐藥性中產(chǎn)生了重要的作用。
- A significant impediment to the success of cancer chemotherapy is multidrug resistance (MDR)and this could be attributable to concomitance of multiple intricate mechanisms. 腫瘤多藥耐藥(MDR)是導致腫瘤化療失敗的主要原因之一,是多種復雜機制共同作用的結果。
- Multidrug resistance(MDR) has become the main hindrance of chemotherapy,and the reversal of MDR is the key point to improve curative effect of chemotherapy. 摘要 腫瘤細胞對化療藥物產(chǎn)生的多藥耐藥(MDR)已成為當前影響腫瘤化學(xué)治療療效的主要障礙,尋找低毒有效的MDR逆轉劑是提高化療療效的關(guān)鍵。
- The aim of this study was to ex amine the reversal effects of high intensity focused ultrasound (HIFU) and co-a dministration with Adriamycin (ADM) on multidrug resistance (MDR) in HepG2/Adm c ells, and to investigate its mechanism. 本研究評價(jià)高強度聚焦超聲及其聯(lián)合阿霉素(Adriamycin,ADM)對人肝癌多藥耐藥細胞株HepG2/Adm的效應,并探討其作用機制。
- Objective To study the effect of hyperthermia on expression of multidrug resistance-related(MDR) proteins and intracellular ADM concentration in tongue squamous cell carcinoma cell line Tca 8113 and its multidrug resistance(MDR) cell line Tca8113/CBDEA. 目的探討熱療對舌鱗癌Tca 8113細胞和耐藥的Tca 8113/CBDEA細胞多藥耐藥蛋白表達和耐藥性的影響。
- Objective: To investigate the relationship between the expression of lung resistance-related protein (LRP)gene and multidrug resistance (MDR)in patients with acute myeloid leukemia(AML). 目的:探討肺耐藥相關(guān)蛋白(Lung reristance-related protein,LRP)基因在急性髓性白血病(Acute myeloid Leukemia,AML)細胞中的表達及其在臨床耐藥、預后判斷方面的意義。
- Objective:To study effect of radiotherapy on expressions of multidrug resistance(MDR) factors and intracellular ADM concentration in tongue squamous cell carcinoma cell line Tca 8113 and its MDR cell line Tca8113/CBDEA. 目的:探討放療對舌鱗癌Tca 8113細胞和耐藥的Tca 8113/CBDEA細胞耐藥性的影響。
- AIM: To study the reversal effects of droloxifene (DRO) on multidrug resistance (MDR) in K562 cell line resistant to adriamycin (ADR). 目的:研究屈洛昔芬(DRO)對耐阿霉素(ADR)K562細胞株(K562/A02)多藥耐藥性(MDR)的逆轉作用及逆轉機制。
- Although P gp expression is not the only mechanism of MDR, but determination of P gp expression might be helpful in making effort to overcome multidrug resistance of bladder cancer. 盡管P-gp表達不是引起多藥耐受性的唯一機理,但它對克服膀胱癌的抗藥性具有重要的臨床價(jià)值。
- Obsjective:To observe the reversal effect of Sangen Mixture(SGM) in multidrug resistant(MDR) cell lines K562/ADR and K562/VCR. 目的:研究三根制劑對多藥耐藥(MDR)細胞株的逆轉作用。
- Conclusion PKC expression was closely related to multidrug resistance phenotype.PKC is probably an important modulator in adjusting MDR expression in renal pelvic and ureteral carcinoma. 結論蛋白激酶C與腎盂輸尿管癌多藥耐藥密切相關(guān),可能是調節腎盂輸尿管癌多藥耐藥的重要因素之一。