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- 乙基紅分光光度法測定鹽酸西布曲明Spectrophotometric Method for Determination of Sibutramine Hydrochloride with Ethyl Red
- 鹽酸西布曲明對營(yíng)養性肥胖大鼠的減肥作用Anti-obesity effect of sibutramine hydrochloride in alimentary obesity rats
- 剛果紅褪色光度法測定鹽酸西布曲明及作用機理研究Fading Spectrophotometric Method for Determination of Sibutramine Hydrochloride with Congo Red and Its Reaction Mechanism
- 含to keep
- 含水watery
- 鹽酸西布曲明sibutramine hydrochloride
- 鹽酸hydrochloric acid
- 含稅價(jià)格price including tax
- 富含be rich in
- N-去二甲基西布曲明(BTS54505)N-di-desmethyl sibutramine (BTS 54505)
- 含水率water ratio
- 方法 :以對氯氰芐為起始原料經(jīng)環(huán)合、格氏反應、還原、氮上的氮甲基化、成鹽 5步反應合成鹽酸西布曲明 ,并對反應的條件進(jìn)行了優(yōu)化。 結果 :經(jīng) 5步反應合成鹽酸西布曲明 ,總收率為 40 6%。OBJECTIVE:To study the synthesis of sibutramine hydrochloride METHODS:Sibutramine hydrochloride was synthesized from the starting material 4 chlorobenzylcyanide by cyclization,Grignard reaction,reduction,methylation to afford sibutramine which followed by salt formation with hydrochloride,the conditions in synthesis were improved RESULTS:Sibutramine hydrochloride was synthesized from 4 chlorobenzylcyanide The overall yield was 40 6%25 CONCLUSION:The methed was more suitable for mass manufacture
- 含油oiliness
- 西布曲明治療6個(gè)月可降低肥胖患者血清游離脂肪酸水平Level of Free Fat Acid Could be Decreased in Obese Subjects after 6 Months'Treatment with Sibutramine
- 內含include
- 西布曲明治療超重和單純性肥胖患者停藥1年后體質(zhì)量的變化Body mass change in overweight and simple obesity patients 1 year after withdrawal of sibutramine
- 鹽酸鹽hydrochloride
- 含沙射影to insinuate
- 西布曲明對肥胖患者糖脂代謝、體脂及胰島素抵抗影響的多中心研究Effects of sibutramine on blood glucose and lipids, body fat mass and insulin resistance in obese patients: a multi-center clinical trial
- 含碳carbonic