It means that except targeted mutation (TM ), there exits non targeted mutation (NTM), which is the result of genetic instability induced by DNA damaging agents.
英
美
- 即DNA損傷劑除了能直接作用于細胞遺傳物質(zhì)而造成損傷部位的定標性突變(targeted mutation,TM)外,還可能通過(guò)誘導某些基因的表達或功能改變導致DNA復制差錯,從而在未損傷部位形成非定標性突變(non targeted mutation,NTM)。