Irrespective of how DNA replication stress is induced,the collapse of DNA replication forks occurs preferentially at specific chromosomal locicalled common fragilesites(23).

 
  • 不管DNA復制應答是怎樣被誘導的,DNA復制叉的崩潰會(huì )有選擇性的發(fā)生在染色體的易碎位點(diǎn)(23)。
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