In eukaryotic cell,ORC1 accumulates in G1 and is degraded in S phase, but other ORC subunits remain at almost constant levels.

 
  • 在真核細胞中ORC1亞基的量在細胞周期中呈現周期性波動(dòng)(G1中期開(kāi)始積累,S期開(kāi)始減少),而ORC2-6在整個(gè)細胞周期保持穩定,這種ORC1的周期性波動(dòng)被稱(chēng)為“ORC1周期”。
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