In conclusion, thrombin can induce GEC proliferation and GEC detachment. The latter is pro bably related to PA mediated over degradation of extracellular matrices such as fibronectin, which are needed for cell attachment.
英
美
- 結論：凝血酶可導致GEC增殖、脫壁，后者可被抑肽酶阻斷，因而很可能與細胞貼壁所必需的FN等細胞外基質(zhì)被升高的PA活性過(guò)度降解有關(guān)。
