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- Objective: To introduce inhaled iloprost for the treatment of primary pulmonary hypertension. 摘要目的:介紹治療原發(fā)性肺動(dòng)脈高壓的吸入性伊洛前列素。
- In 9 patients on chronic intravenous prostanoids, 8 transitioned from intravenous prostanoids to inhaled iloprost, which continued during follow-up. 9例長(cháng)期靜脈應用類(lèi)前列腺素的患者中,8例從靜脈應用類(lèi)前列素改為吸入伊洛前列素并且在隨訪(fǎng)期間一直持續應用。
- Results and Conclusion: Inhaled iloprost can reduce pulmonary vascular resistance and delay the development of primary pulmonary hypertension. 結果和結倫:吸入性伊洛前列素治療可以降低肺血管阻力和延緩原發(fā)性肺動(dòng)脈高壓的進(jìn)程。
- Background: Inhaled iloprost has been approved for the treatment of adults with PAH, but little is known about the effects in children with PAH. 背景:吸入伊洛前列素被證實(shí)可用于治療成人PAH,但其對兒童PAH的作用尚不清楚。
- Conclusion Inhaling iloprost and pulmonary injection of phentolamine can both effectively differentiate the functional and occlusive PAH in CHD. 酚妥拉明用藥前后,肺循環(huán)和體循環(huán)的壓力、阻力和血流量都有明顯變化。
- Results and Conclusion:Inhaled iloprost can reduce pulmonary vascular resistance and delay the development of primary pulmonary hypertension. 結果和結論:吸入性伊洛前列素治療可以降低肺血管阻力和延緩原發(fā)性肺動(dòng)脈高壓的進(jìn)程。
- Conclusions: Inhaled iloprost caused sustained functional improvement in some children with PAH, although inhaled iloprost occasionally induced bronchoconstriction. 結論:吸入伊洛前列素對部分PAH兒童有長(cháng)期的功能改善,雖然偶爾導致支氣管收縮。
- Of those patients, 32 were selected to receive inhaled iloprost (a prostacyclin analog) along with bosentan, while the remainder took a placebo and bosentan. 在這些病人中,32例采用吸入性伊洛前列素(一種前列腺幻素的類(lèi)似物)和波生坦的聯(lián)合用藥,其余病人采用安慰劑和波生坦治療。
- Acute iloprost inhalation reduced forced expiratory volume in 1 s and mid-volume forced expiratory flow by 5% and 10%, respectively, consistent with acute bronchoconstriction. 急性伊洛前列素吸入分別降低1秒用力呼氣量和呼氣中段流速5%25和10%25,與急性支氣管收縮一致。
- Sixty-four percent of patients continued receiving long-term iloprost therapy, 36% stopped iloprost, due to lower airway reactivity, clinical deterioration, or death. 64%25患者繼續使用長(cháng)期伊洛前列素吸入、36%25患者因為低氣道反應性、臨床惡化或死亡而停止使用伊洛前列素。
- Results: Acute administration of inhaled iloprost lowered mean pulmonary artery pressure equivalent to the response to inhaled nitric oxide with oxygen. 結果:吸入伊洛前列素對肺動(dòng)脈壓力的降低與吸入一氧化氮加氧氣的作用相等。
- Zangeler E G, Hinsbergh V W. Norepinephrine and iloprost improve barrier function of human endothelial cell monolayers. Role of cAMP\[J\]. Am J Physiol 1994,260(5):c1052-1058. 黃嶄;陳凇娟.;卡維地洛治療高血壓的臨床療效及對血脂、糖代謝的影響\\[J\\]
- Cardiac catheterization, standard lung function testing before and after iloprost inhalation, 6-min walk test, World Health Organization functional class, and hemodynamic parameters were monitored. 研究監測了吸入前后的心導管檢查、標準肺功能檢查,6分鐘步行實(shí)驗、世界衛生組織功能分級和血流動(dòng)力學(xué)指標。
- Keywords iloprost;administration;inhalation;review;hypertension;pulmonary; 伊洛前列素;投藥;吸入;綜述;高血壓;肺性;
- Keywords partial liquid ventilation;perfluorocarbon;acute lung injury;iloprost; 部分液體通氣;全氟化碳;急性肺損傷;伊洛前列素;
- Inhaled iloprost in eight heart transplant recipients presenting with post-bypass acute right ventricular dysfunction 對八例行心臟移植術(shù)、轉流后出現急性右心室功能不全的患者吸入依洛前列素的報道
- Ilomedin 伊落前列素, 伊洛前列[周?chē)軘U張藥]
- Keywords acute lung injury;acute respiratory distress syndrome;perfluorocarbon;partial liquid ventilation;Iloprost;hypoxemia;pulmonary hypertension; 急性肺損傷;急性呼吸窘迫綜合征;部分液體通氣;油酸;伊洛前列素;低氧血癥;氧合指數;肺靜態(tài)順應性;
- iloprost 伊洛前列素<前列腺素類(lèi)藥>