High glucose promote the maturation of MDCs and augment their capacity to stimulate T-cell proliferation and cytokine secretions at least in part through enhancing intracellular ROS generation.

 
  • 高糖顯著(zhù)增強樹(shù)突狀細胞內ROS,從而促進(jìn)樹(shù)突狀細胞成熟,激活T淋巴細胞的能力也明顯增強,并且通過(guò)促進(jìn)樹(shù)突狀細胞本身釋放一些炎癥因子,加速和放大炎癥免疫反應。
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