HR can repair the DNA double strand breaks (DSBs) which is the most severe damage of DNA. It is not known whether Hp induce the occurrence of GCa by inhibiting the functions of BER genes and HR genes?
英
美
- HR是真核細胞修復DNA雙鏈斷裂(DNA double strand breaks, DSBs)的一個(gè)重要途徑, HR相關(guān)基因的缺陷可引起DSBs修復減少,腫瘤發(fā)生率顯著(zhù)增加。
