Gel filtration chromatography of tumor extract demonstrates a single major peak of bone resorption activity (BRA, 45Ca release from calvarial bone) that elutes with an apparent MW of about 15,000 dalton.

 
  • 腫瘤提取液經(jīng)ultrogel層析,發(fā)觀(guān)僅有一溶骨活性峰(~(45)Ca自乳鼠頂骨培養中的釋出率),相當于表觀(guān)分子量15,000道爾頓。
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