Examination of nuclear extracts revealed that young cells had a higher increase in the amount of p-Stat3 in the nuclei than in that of senescent cells, suggesting a failure to translocate phosphorylated StatS to the nucleus in senescent cells.
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- 應用Northern blotting檢測了年輕細胞和衰老細胞中Stat3 mRNA的表達，結果發現衰老細胞中Stat3 mRNA的表達與年輕細胞比無明顯的差別，而Western blotting示衰老細胞中Stat3蛋白的第四軍醫大學博士研究生論文表達明顯高于年輕細胞，其活性形式磷酸化的Stat3中Stat3）的表達也不低于年輕細胞；
