Electrophoresis mobility shift assay(EMSA)showed that both NPs of Z10 and Z37 hantaviruses bound specifically to the double-stranded DNA probe possessing the 18-nucleotide inverted repeat sequences in vitro.

 
  • 然后將該探針與純化的Z10、Z37株的核蛋白NP進(jìn)行非變性凝膠電泳遷移改變實(shí)驗(EMSA)后發(fā)現,重組的Z10、Z37株的核蛋白NP,在體外均可特異地結合其基因組末端反向重復序列形成的雙鏈探針。
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