Defects of mitotic spindle assembly in the cells of children with MVA produce random aneuploidies throughout their bodies, and nearly one third develop leukemia or unusual solid cancers.

 
  • 也因此,這些改變代表了存活下來(lái)的非整倍體細胞要走上腫瘤增生之路,必須具有的最起碼變化。
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