DNA methylation catalyzed by DNA methyltransferases interacts with histone modification to inhibit gene transcription,induce gene silencing at the participation of many regulators.

 
  • DNA甲基化由DNA甲基轉移酶催化,在多種調節因子的參與下,與組蛋白修飾相互作用,抑制基因轉錄,導致基因沉默。
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