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- Over 11 known Fanconi anemia gene products are involved in DNA damage response pathway. 目前已發(fā)現11種FA蛋白參與形成了一種DNA損傷應答途徑。
- Two proteins found on telomeres control DNA damage response pathways 在端粒上發(fā)現兩種控制DNA損傷反應通路的的蛋白質(zhì)
- We are particularly interested in the roles of chromatin modifications in DNA damage response. 我們的一個(gè)研究重點(diǎn)是染色質(zhì)修飾在DNA損傷反應中的作用。
- A large amount of evidence has implicated BRCA1 in multiple cellular functions including DNA damage response, transcriptional regulation, and control of centrosome duplication. 有大量的證據表明BRCA1具有有很多功能,包括DNA損傷反應,轉錄調控和控制中心體的復制。
- Regulated in development and DNA damage responses REDD1
- We have designed a strategy to select new drug targets that inhibit a cellular gene required for HBV replication or restore a response stalled by HBV in the ATR DNA damage pathway. 篩選新的藥物靶點(diǎn)可以通過(guò)抑制HBV復制必需的一個(gè)基因或者保持HBV所引起的ATR損傷途徑中的一種失調反應。
- Exploiting the activation of the DNA damage pathway by viral replication for the generation of antiviral drugs needs to be examined. 利用病毒復制激活DNA修復途徑而制成的抗病毒藥物需要進(jìn)一步檢測。
- Curbing DNA damage might make cancer less likely. 卷曲的DNA損傷導致癌癥也很少。
- Catechins may also prevent DNA damage caused by carcinogens. 兒茶酚還可能預防致癌物質(zhì)引起DNA損傷。
- GEN caused DNA damage but not due to oxidant effect. GEN導致細胞DNA斷裂,但不是由其氧化效應引起。
- Both UV-A and UV-B irradiation induced DNA damage in mesophylls. 彗星檢測結果表明,九里香葉片DNA的損傷程度與UV-B輻射的劑量呈正相關(guān);
- Ethanol extract of adzuki bean has the estrogen-like activities through the estrogen response pathway. 赤豆提取物具有雌激素活性,此作用是通過(guò)雌激素受體(ER)介導的。
- Using such an early donor cell might avoid the risk of accumulated DNA damage. 使用這樣的一個(gè)早期供體細胞可能避免積聚DNA損傷的風(fēng)險。
- As ethylene is a versatile phytohormone, its response pathway has multiple interactions (crosstalk) with other signaling pathway. 由于乙烯是一種多功能的植物激素, 其信號途徑與其它信號途徑有多重的交叉。
- The DNA damage become more serious as the dose of 1,2,4 - TCB increases. 隨著(zhù)染毒劑量增加,DNA損傷加重。
- DNA damage by mutagens has very serious consequences for DNA replication. 試比較切除修復和光復活機制是如何清除由紫外線(xiàn)誘導形成的嘧啶二聚體的?
- DNA damage responses DNA損傷反應
- Several of the genes that the scientists identified as being involved in aging are also connected to a key nutrient response pathway known as known as the Target of Rapamycin, or TOR. 幾個(gè)被科學(xué)家們認定與老化有關(guān)的基因還連接著(zhù)一個(gè)叫雷帕霉素靶蛋白的營(yíng)養反應通路(TOR)。
- It is concluded that the nuclear focus formation of hMRE11 protein may be a response to DNA damage induced by topoisomerase II inhibitor VP-16 in human promonocytic cell line U937. 結論:hMRE11蛋白核灶形成可能參與VP-16所致人單核白血病細胞株U937的DNA損傷修復過(guò)程。
- Conclusion: Garlic oil can prevent WBC decrease and DNA damage induced by radiation. 結論:大蒜油具有對抗輻射引起的白細胞減少和DNA損傷作用。